transcription repression meaning in Chinese

转录阻抑

Examples

The identified proteins are involved in a variety of cellular process including several zinc finger proteins relevant to transcription regulation , such as zinc finger 198 , 263 , 14 , 224 , zf6 , novel protein similar to transcriptional represser ctcf , and kruppel - like zinc finger protein ; two members of the adams ( a disintegrin and metalloprotease domain ) family ; two members of integrin family ; several proteins involved in the signal transduction , cell - cycle control , chromatin remodeling and transcription repression ; and also some proteins of cell skeleton and some with unknown functions
鉴定出的蛋白包括多个与转录调控相关的锌指蛋白，如锌指蛋白198 、 263 、 14 、 224 、 zf6 、转录抑制因子ctcf样蛋白、幻肚pple样锌指蛋白等:两个含金属蛋白酶结构域和整合素结合结构域的家族成员adam28和adam17 ;两个整合素家族成员pz整合素和含十个egf样结构域的整合素( tied ) ;与细胞信号转导通路有关的蛋白;与细胞周期调控有关的蛋白;与染色体重塑和基因转录抑制有关的蛋白;细胞骨架蛋白以及其他功能未明的蛋白等。
To search proteins that associate with the mouse mint protein and regulate notch signaling in nuclei , and to study the function and mechanism of mint - mediated transcription repression , yeast two - hybrid assay was used to screen proteins that interact with a fragment of mint ( f5 , amino acids 2226 - 2959 ) . from 4x106 yeast clones transformed with the bait plasmid and a cdna library of 9 dpc mouse embryo , fifty - one were positive for nutritional screening and p - galactosidase assay . restriction digestion identified 10 independent positive clones and these were analyzed by dna sequencing these clones represent 3 correctly fused cdna fragments , which are mint , alpha a - crystallin - binding protein i ( alphaa - crybpl ) , and nuclear receptor co - repressor 1 ( n - corl ) , respectively
鉴于mwt基因编码区较长，共有10799个碱基，故此我们将mint分为六段，分别命名为fi一f6 ，本研究以其中的f5 （ 222e959 ）和f6 （ 296s576 ）片段为研究对象，将h者分别插入pgb盯7载体中，结果显示： mintfs可与核受体辅助抑制因子1阶cori ）， o晶状体蛋白结合蛋白1hlphatcrybp入及mw加互作用，而f6可与igm的重链恒定区、泛素结合酶2l6和一个未知功能的新的蛋白基因进行结合。

transcription repression meaning in Chinese

Examples

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